Publikationen

Begutachtete Fachartikel, Konferenzbeiträge und Abstracts, Übersichtsarbeiten und Open-Source-Code aus den Multi-dimensionAI-Arbeitsgruppen in Heidelberg, Mainz und München.

Neuigkeiten

  • 2026

    Deep learning-based echocardiography for cardiac assessment: a systematic literature review and meta-analysis

    Romano-Martinez, A., Zeid, S., Krolevets, M., Kontohow-Beckers, K., ten Cate, V., Lurz, P., … Wild, P. S.

    European Heart Journal – Digital Health, 7(9), ztag148

  • 2026

    Visual prompt engineering for multimodal and irregularly sampled medical data

    Tölle, M., Scharaf, M., Fischer, S., Reich, C., Zeid, S., Dieterich, C., … Engelhardt, S.

    Communications Medicine, 6, 474

Journal-Artikel

  1. 2026

    Deep learning-based echocardiography for cardiac assessment: a systematic literature review and meta-analysis

    Romano-Martinez, A., Zeid, S., Krolevets, M., Kontohow-Beckers, K., ten Cate, V., Lurz, P., … Wild, P. S.

    European Heart Journal – Digital Health, 7(9), ztag148

  2. 2026

    Visual prompt engineering for multimodal and irregularly sampled medical data

    Tölle, M., Scharaf, M., Fischer, S., Reich, C., Zeid, S., Dieterich, C., … Engelhardt, S.

    Communications Medicine, 6, 474

  3. 2026

    Enhancing sit-to-stand transitions and walking efficiency in older adults with a soft robotic suit

    Zhang, X., Tricomi, E., Stefanakis, M., Gierden, N., Buchner, T., Mišković, L., … Masia, L.

    Nature Communications, 17, 6540

  4. 2026

    ParTIpy: a scalable framework for archetypal analysis and Pareto task inference

    Schäfer, P. S. L., Zimmermann, L., Burmedi, P. L., Walfisch, A., Goldenberg, N., Yonassi, S., … Saez-Rodriguez, J.

    Molecular Systems Biology, 22(8), 1252–1269

  5. 2026

    Deformable image registration for self-supervised cardiac phase detection in cardiac magnetic resonance images of patients with various diseases

    Mueller, S. K., Koehler, S., Kiekenap, J., Greil, G., Hussain, T., Sarikouch, S., … Engelhardt, S.

    Medical Image Analysis, 113, 104142

  6. 2026

    Chronotropic response in heart failure: clinical, structural, and metabolic predictors and long-term mortality

    Bélanger, N., Zeid, S., Gieswinkel, A., Kazemi-Asrar, F., Velmeden, D., Rausch, F., … Wild, P. S.

    European Journal of Heart Failure, xuag139

  7. 2026

    Performance of large language models in delivering accurate and comprehensible patient information on heart failure and cardiomyopathy

    Reich, C., Leverenz, J., Brand, C., Niemeier, L., Branzei, I., Yildirim, M., … Meder, B.

    Frontiers in Digital Health, 8, 1847603

  8. 2026

    Comparison and optimization of cellular neighbor preference methods for quantitative tissue analysis

    Schiller, C., Ibarra-Arellano, M. A., Bestak, K., Tanevski, J., Schapiro, D.

    Nature Communications, 17, 3514

  9. 2026

    Multiplexed imaging reveals immune-metabolic niches in multiple myeloma linked to progression and bone disease

    Roseth, I. A., Hatscher, L., Schiller, C., Johnstuen, H. S. S., Slørdahl, T. S., Hov, H., Schapiro, D., Standal, T.

    Blood Cancer Discovery, 7(3), 460–478

  10. 2025

    The European BestAgeing Study on microRNA candidates reveals distinct signatures with diagnostic and prognostic potential in cardiovascular disease

    Reich, C., Kayvanpour, E., Sedaghat-Hamedani, F., Amr, A., Haas, J., Ueltzhöffer, K., … Meder, B.

    BMC Medicine, 23, 670

  11. 2025

    Spatial multiomics of acute myocardial infarction reveals immune cell infiltration through the endocardium

    Wünnemann, F., Sicklinger, F., Bestak, K., Nimo, J., Thiemann, T., Amrute, J. M., … Schapiro, D.

    Nature Cardiovascular Research, 4, 1345–1362

  12. 2025

    Unconditional latent diffusion models memorize patient imaging data

    Dar, S. U. H., Seyfarth, M., Ayx, I., Papavassiliu, T., Schoenberg, S. O., Siepmann, R. M., … Engelhardt, S.

    Nature Biomedical Engineering, 10, 458–472

  13. 2025

    Medication information extraction using local large language models

    Richter-Pechanski, P., Seiferling, M., Kiriakou, C., Schwab, D. M., Geis, N. A., Dieterich, C., Frank, A.

    Journal of Biomedical Informatics, 169, 104898

  14. 2025

    ECG synthesis and utility analysis – a diffusion model based approach

    Hegde, S., Prüser, M., Cenic, N., Bollinger, A., Arens, M., Köhlen, J., Martens, E., Dieterich, C.

    Studies in Health Technology and Informatics, 331, 346–356

  15. 2025

    Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target

    Llaó-Cid, L., Wong, J. K. L., Fernandez Botana, I., Paul, Y., Wierz, M., Pilger, L.-M., … Seiffert, M.

    Nature Communications, 16, 7271

Konferenzbeiträge

  1. Vorschaubild der Projektseite zu VolDiT
    2026

    VolDiT: controllable volumetric medical image synthesis with diffusion transformers

    Seyfarth, M., Dar, S. U. H., Frisch, Y., Wild, P. S., Frey, N., André, F., Engelhardt, S.

    MICCAI 2026, 27. Sep. – 1. Okt. 2026

  2. Vorschaubild der Projektseite zu CardioDiT
    2026

    CardioDiT: latent diffusion transformers for 4D cardiac MRI synthesis

    Seyfarth, M., Müller, S. K., Ghanaat, A., Ayx, I., Fastenrath, F., Wild, P. S., … Engelhardt, S.

    MICCAI 2026, 27. Sep. – 1. Okt. 2026

  3. 2026

    Active soft hip exosuit with quasi-passive clutch mechanism for bidirectional assistance

    Urban, J., Miskovic, L., Tricomi, E., Masia, L.

    BioRob 2026, 1.–4. Aug. 2026

  4. 2026

    User-tailored learning to forecast walking modes for exosuits

    Abbate, G., Tricomi, E., Gierden, N., Giusti, A., Masia, L., Paolillo, A.

    IEEE International Conference on Robotics and Automation (ICRA 2026), Wien, 1.–5. Juni 2026

  5. 2026

    Voice-driven assistance and resistance modulation in a soft hip exosuit using a transformer-based speech recognition model

    Tricomi, E., Lindner, D., Zhang, X., Miskovic, L., Masia, L.

    IEEE International Conference on Robotics and Automation (ICRA 2026), Wien, 1.–5. Juni 2026

  6. 2026

    Rethinking diversity metrics in medical imaging with Wasserstein distance

    Seyfarth, M., Dar, S., Engelhardt, S.

    Bildverarbeitung für die Medizin (BVM) 2026, Informatik aktuell, S. 420–426 · Poster

  7. 2025

    MedLoRD: a medical low-resource diffusion model for high-resolution 3D CT image synthesis

    Seyfarth, M., Dar, S. U. H., Ayx, I., Fink, M. A., Schoenberg, S. O., Kauczor, H.-U., Engelhardt, S.

    SASHIMI Workshop at MICCAI 2025, Lecture Notes in Computer Science, S. 1–12 · Best Reproducibility Award

  8. 2025

    An automatic self-supervised phase-based approach to aligned long-axis strain measurements in four chamber cardiovascular magnetic resonance imaging

    Mueller, S. K., Kiekenap, J., Koehler, S., Andre, F., Frey, N., Greil, G., … Engelhardt, S.

    Functional Imaging and Modeling of the Heart (FIMH 2025), Dallas, LNCS 15673, S. 113–125

  9. 2025

    ThermoCycleNet: stereo-based thermogram labeling for model transition to cycling

    Andrés López, D., Weber, V., Zentgraf, S., Hillen, B., Simon, P., Schömer, E.

    18th International Work-Conference on Artificial Neural Networks (IWANN 2025), A Coruña, 16.–18. Juni 2025 · Vortrag

  10. 2024

    Latent pollution model: the hidden carbon footprint in 3D image synthesis

    Seyfarth, M., Dar, S. U. H., Engelhardt, S.

    SASHIMI Workshop at MICCAI 2024, Marrakesh, Lecture Notes in Computer Science, S. 146–156

Abstracts und Poster

ESC Digital & AI Summit 202612.–13. Nov. 2026Demnächst

  1. Deep learning based automatic temporally aligned atrial strain from four chamber cine cardiac MRI

    Müller, S. K., Fischer, S., Kiekenap, J., Koehler, S., Andre, F., Hussain, T., … Engelhardt, S.

  2. An LLM-native wiki knowledge graph for HFpEF: structured, traceable clinical question answering in a complex cardiovascular syndrome

    Müller, S. K., Seyfarth, M., Kiekenap, J., Fischer, S., Zeid, S., Wild, P. S., Frey, N., Engelhardt, S.

  3. AI-agent-driven autonomous research loop for cardiac MRI deep learning model optimization

    Seyfarth, M., Dar, S. U., Engelhardt, S.

  4. Replacing the people who promised to replace clinicians: autonomous AI-agents for cardiac MRI segmentation

    Seyfarth, M., Engelhardt, S., Dar, S.

  5. Deep learning-based carotid ultrasound analysis identifies molecular mechanisms of accelerated vascular aging

    ten Cate, V., Gul, G., Balada, C. P., Romano Martinez, A., Zeid, S., Dengel, A., Lurz, P., Wild, P. S.

  6. Assessment of physical activity in HFpEF: comparing digital mobility outcomes, cardiopulmonary exercise test and six-minute walk test

    Kerber, A., Zeid, S., Chalabi, J., Söhne, J., Velmeden, D., Fooß, B., … Wild, P. S.

  7. Real-world performance of an A4C deep-learning algorithm for detection of cardiac amyloidosis in echocardiography

    Leverenz, J., Reich, C., Roßkopf, S., aus dem Siepen, F., Nagel, C., Hund, H., … Meder, B.

  8. Putting ECG foundation models to real-world data test: a prognostic prediction of major adverse cardiovascular events

    Moderierte PosterpräsentationHegde, S., Prüser, M., Merzweiler, A., Heuschmann, P., Dieterich, C.

  9. Federated GWAS enables privacy-preserving multi-center genomic analysis – the DZHK cardiovascular cohort as show case

    PosterSergei, G., Dieterich, C., Akgun, M., Swaminathan, A.

Benzon AI Symposium 2026, Kopenhagen7.–10. Sep. 2026

  1. Mapping seven decades of cardiomyopathy: a transformer-based analysis of 151,109 publications

    Reich, C., Dönmez Yalcin, G., Sedaghat-Hamedani, F., Amr, A., Frey, N., Meder, B.

ESC Congress 2026

  1. A plasma metabolite profile predicts worsening of heart failure and reflects distinct inflammatory mechanisms in symptomatic heart failure

    Yapıcı, E., Zeid, S., Martens, R., Nguyen, S., Koeck, T., ten Cate, V., Schmidlin, T., Wild, P. S.

  2. DNA methylation patterns predict primary myocardial infarction

    Ingold, M., Müller, C., Krolevets, M., Yapici, E., Rapp, S., Pfeiffer, N., … Wild, P. S.

ESSB Conference 2026

  1. Spatial organization of T cell populations in NSCLC brain metastases

    PosterChazotte, M., Pilger, L.-M., Schniederjohann, C., Dietrich, S., Seiffert, M., Schapiro, D.

ESC Digital & AI Summit 2025, Berlin21.–22. Nov. 2025

Die Abstracts wurden im European Heart Journal – Digital Health, Band 7, Supplement (2026), veröffentlicht.

  1. Beyond visual realism: assessing coronary artery dominance diversity in AI-generated synthetic coronary computed tomography angiography images

    Ghanaat, A., Seyfarth, M., Ayx, I., Schoenberg, S. O., Engelhardt, S., Dar, S.

  2. Latent diffusion for single-pass full 4D cine cardiac magnetic resonance imaging synthesis with spatiotemporal autoencoding

    Seyfarth, M., Mueller, S. K., Dar, S., Engelhardt, S.

  3. Predicting worsening and mortality in heart failure: a novel deep learning approach using echocardiographic data outperforms established biomarkers

    Romano-Martinez, A., Kontohow-Beckers, K., Zeid, S., Krolevets, M., Mueller, S. K., Lurz, P., … Wild, P. S.

  4. Myocardial motion curves from CMR: an automated approach to visualize complex deformation patterns and comparison of healthy and diseased cohorts

    Kiekenap, J., Mueller, S. K., Köhler, S., Frey, N., Engelhardt, S.

  5. Deep neural network-driven infrared thermography for diagnostics and therapy monitoring of peripheral arterial disease

    Hillen, B., Schäffer, L. C., Andrés López, D., Weber, V., Zentgraf, S., Schömer, E., … Simon, P.

ESC Congress 202529. Aug. – 1. Sep. 2025

  1. Deep learning-based prediction of cardiac blood biomarkers from echocardiograms improves prognosis

    PosterRomano-Martinez, A., Kontohow-Beckers, K., Zeid, S., Mueller, S. K., Prochaska, J. H., Lurz, P., … Wild, P. S.

Heart Failure 2025 (48th Heart Failure Congress)17.–20. Mai 2025

  1. Deep learning by vision transformer-based assessment of image quality in echocardiography improves prediction of heart failure-specific outcome

    PosterRomano-Martinez, A., Kontohow-Beckers, K., Zeid, S., Mueller, S. K., Prochaska, J. H., Lurz, P., … Wild, P. S.

ESSB Conference 2025

  1. spCellEval (spatial proteomics cell phenotyping evaluation): benchmarking cell-phenotyping methods for antibody-based multiplexed imaging

    PosterHada, A., Hatscher, L., Chazotte, M., Tanevski, J., Schapiro, D.

Übersichtsarbeiten und Kommentare

  1. 2026

    Igniting the future of cardiovascular care: highlights from the ESC Digital and AI Summit 2025 in Berlin

    Engelhardt, S., Bruining, N., Asselbergs, F. W.

    European Heart Journal, ehaf1068

  2. 2025

    Artificial intelligence to improve cardiovascular population health

    Meder, B., Asselbergs, F. W., Ashley, E., et al.

    European Heart Journal, 46(20), 1907–1916

  3. 2025

    Präzisionsmedizin bei Diagnostik und Therapie von Kardiomyopathien

    Vetter, N., Meder, B.

    Herz, 50, 96–102

  4. 2024

    Artificial intelligence in cardiovascular imaging and intervention

    Engelhardt, S., Dar, S. U. H., Sharan, L., et al.

    Herz, 49, 327–334

  5. 2024

    Healthcare 4.0 – Medizin im Wandel

    Roßkopf, S., Meder, B.

    Herz, 49, 350–354

Quellcode

  • VolDiT ↗Steuerbare Erzeugung dreidimensionaler medizinischer Bilder mit Diffusions-Transformern (MICCAI 2026)Mai 2026
  • CardioDiT ↗Latente Diffusions-Transformer zur Erzeugung zeitaufgelöster dreidimensionaler Herz-MRT-Bilder (MICCAI 2026)Mai 2026
  • wad-div ↗Maße für die Vielfalt medizinischer Bilder auf Basis der Wasserstein-Distanz (BVM 2026)März 2026
  • cmr-multi-view-phase-detection ↗Selbstüberwachtes Lernen zur Erkennung von Phasen des Herzzyklus in Herz-MRT-Bildern (Medical Image Analysis 2026)Nov. 2025
  • MedLoRD ↗Ressourcenschonendes Diffusionsmodell zur Erzeugung hochauflösender dreidimensionaler CT-Bilder (SASHIMI 2025)März 2025
  • cmr-las-phase2phase-analysis ↗Messung der Längsdehnung im Vierkammerblick der Herz-MRT mit phasenbasierter Ausrichtung (FIMH 2025)2025

Auszeichnungen

  • Best Reproducibility Award

    SASHIMI Workshop, MICCAI 2025, Südkorea

    Ausgezeichnete Arbeit: MedLoRD: a medical low-resource diffusion model for high-resolution 3D CT image synthesis · Marvin Seyfarth, Dr. Salman Dar (Arbeitsgruppe von Sandy Engelhardt)

  • Best Poster of the Day Award

    DGK-Jahrestagung 2026, Mannheim

    Ausgezeichnete Arbeit: Targeted plasma profiling of the proteomic response to physical activity in HFpEF

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